Because of social media, the evil and wrongdoers also have got a way to express their hate openly. I come across people abusing Islam, our Holy Prophet (pbuh), Mecca, Medina which is incurred extremely hurtful and also angers a lot. What should be our reaction? Should we leave it to Allah and do sabr?

We should positively try counter this negativity. Many people are ignorant. If we show them the proofs effectively they accept. Do your best in positively responding to them. It has an effect