1. Answer: From Ayatollah Sayed Sistani’s website
Question: I am living in India and I have a lot of doubts about things I am using and I eating. What is my duty about such things?
Answer: A well known religious law says: "Everything is ritually pure for you unless you come to know that it is ritually impure." This law declares everything to be pure unless one becomes sure a particular item has become impure. And as long as you are not sure that it has become ritually impure (najis), it is to be considered pure and you can apply all the rules of purity to it without any hesitation or doubt.
2. Your hand has najasat on it and touches another thing this thing becomes mutanajis then this thing touches another thing while wet that thing becomes mutanajis but after that it does not transfer
3. The leftover water from ghusl is not najis
4. According to Ayatollah Sayed Sistani If the probability of the leather originating from a zabiha (an animal slaughtered Islamically) source is so weak that people would not normally give any credence (for example, the probability of 2%), it is to be considered impure and this cannot be used in salat. But if the probability is not so weak, it can be considered pure and using it in salat would be permissible.
5. Being a Muslim you should assume he has taken the proper steps to clean your area and consider the area pure unless you become certain it is najis