This is the common challenge for every person, to let go of the personal ego and submit to Allah. Moreover, we must search for our own shortcomings and recognize that we may have caused hurt to others.
If prayers and supplication cannot solve the issue then sometimes we need help from professionals who can work out the cause of the issue and provide a suitable way to resolve it.
Recite a lot of astaghfar and the following
وَمَنْ يَتَّقِ اللَّهَ يَجْعَلْ لَهُ مَخْرَجًا * وَيَرْزُقْهُ مِنْ حَيْثُ لَا يَحْتَسِبُ وَمَنْ يَتَوَكَّلْ عَلَى اللَّهِ فَهُوَ حَسْبُهُ إِنَّ اللَّهَ بَالِغُ أَمْرِهِ قَدْ جَعَلَ اللَّهُ لِكُلِّ شَيْءٍ قَدْرًا {الطلاق:2-3}