Our relative an elderly lady wears (removed) dupatta she is widow and has a mental and physical handicap (removed) in (removed) is it ok to give to an agent (another family member) who gives her the money in installments. That is if I give 500$ in khums the agent gives her 100$ each month . Is this allowed or is agent supposed to give lumpsome?

First to give Khums from the portion of sayed if she was needy sayed then it’s ok, otherwise the portion of imam af requires the permission from the marje.
As far as the agency fee, if there is a source who could donate the agency fee which is quite a lot then one should avoid giving such huge amount of the agency fee, small amounts of agency fee are allowed such as 20-30$ on such amounts.
Allah swt knows best.