We wanted to find out more on verse 33:33. How pure were the holy household? Did they perform natural human calls, doing ghusl, state of junoob, haidh/nifas ? As the ayat mentions of them being purified of thorough purification?
And does this apply to all 14 masumeen? How about their spouses and other children who did not become an Imam? And how about prophets wives?

This verse applies to only 14 infallibles. There were purified throughly from any form of sin.
Their wives and children are not included in this verse.